CareLit · DOI-Nachweis · Klinische Pädiatrie
Parvovirus H-1 (H-1PV) exerts oncolytic effects in cell culture models of human brain tumor-initiating cells
DOI 10.1055/s-0032-1320177
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Lacroix, R Josupeit, S Kern, C Herold-Mende, F Schlund, H Witt, T Milde, B Leuchs, SM Pfister, O Witt, JR Schlehofer, J Rommelaere
ZeitschriftKlinische Pädiatrie
Ausgabe11/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Oncolytic virotherapy with H-1PV represents a new therapeutic option for malignant brain tumors currently under clinical investigation in a phase I/IIa H-1PV trial on primary progressive or recurrent glioblastoma. Brain tumor-initiating cells such as glioblastoma „stem-like” cells or medulloblastoma-initiating cells are known to be relatively resistant to conventional anti-neoplastic agents and are thoug…
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Zitierempfehlung
J Lacroix, R Josupeit, S Kern, C Herold-Mende, F Schlund, H Witt, T Milde, B Leuchs, SM Pfister, O Witt, JR Schlehofer, J Rommelaere (2012) Parvovirus H-1 (H-1PV) exerts oncolytic effects in cell culture models of human brain tumor-initiating cells. Klinische Pädiatrie (11). https://doi.org/10.1055/s-0032-1320177
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