CareLit · DOI-Nachweis · Klinische Pädiatrie
Nestin protein expression is an independent prognostic marker in ependymoma and discriminates WHO II ependymoma with poor outcome
DOI 10.1055/s-0032-1320179
Bibliografische Angaben
Nachweis in CareLit
Autor:innenT Milde, T Hielscher, H Witt, M Kool, SC Mack, HE Deubzer, I Oehme, M Lodrini, A Benner, MD Taylor, A von Deimling, AE Kulozik, SM Pfister, O Witt, A Korshunov
ZeitschriftKlinische Pädiatrie
Ausgabe11/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
We have previously shown that the ependymoma cancer stem cell model DKFZ-EP1NS recapitulate ependymoma tumorigenesis at the histological, molecular and clinical level in an orthotopic murine model. EP1NS cells are characterized by a high expression of the neuronal stem cell marker nestin and a stem cell expression signature. We have therefore examined nestin expression in a large cohort of 379 ependymoma primary tum…
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Zitierempfehlung
T Milde, T Hielscher, H Witt, M Kool, SC Mack, HE Deubzer, I Oehme, M Lodrini, A Benner, MD Taylor, A von Deimling, AE Kulozik, SM Pfister, O Witt, A Korshunov (2012) Nestin protein expression is an independent prognostic marker in ependymoma and discriminates WHO II ependymoma with poor outcome. Klinische Pädiatrie (11). https://doi.org/10.1055/s-0032-1320179
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