CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Protective effects of FXR on hepatic lipid accumulation are mediated by hepatic FXR and independent of intestinal FGF15 signal
DOI 10.1055/s-0032-1322347
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Nachweis in CareLit
Autor:innenJ Schmitt, B Kong, B Stieger, O Tschopp, SM Schultze, JC Mertens, P Frei, A Weber, B Müllhaupt, GL Guo, A Geier
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: NALFD represents a chronic liver disease and cofactor in other metabolic diseases with worldwide growing incidence. There is growing evidence confirming a functional interaction between FXR-pathways and hepatic triglyceride metabolism. Methods: Liver- and intestine- specific Fxr knockout mice were under 1% cholesterol diet for 28 days or under a high fat diet. Histological examination of frozen tissue se…
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Zitierempfehlung
J Schmitt, B Kong, B Stieger, O Tschopp, SM Schultze, JC Mertens, P Frei, A Weber, B Müllhaupt, GL Guo, A Geier (2012) Protective effects of FXR on hepatic lipid accumulation are mediated by hepatic FXR and independent of intestinal FGF15 signal. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0032-1322347
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