CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Impact of genetic SLC28 transporter and ITPA variants on ribavirin serum level, hemoglobin drop and therapeutic response in patients with HCV infection
DOI 10.1055/s-0032-1322379
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Rau, F Stickel, S Russmann, M Weisskopf, J Schmitt, MT Dill, JF Dufour, D Moradpour, D Semela, B Müllhaupt, A Geier
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Treatment of chronic hepatitis C is evolving, and DAAs are now added to Peg-INF-α and RBV for the treatment of HCV GT 1 infection. DAAs cause side effects and can even worsen RBV induced hemolytic anemia. Therefore, identifying host genetic determinants of RBV bioavailability and therapeutic efficacy will remain crucial for individualized treatment. Recent data showed associations between RBV induced hem…
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Zitierempfehlung
M Rau, F Stickel, S Russmann, M Weisskopf, J Schmitt, MT Dill, JF Dufour, D Moradpour, D Semela, B Müllhaupt, A Geier (2012) Impact of genetic SLC28 transporter and ITPA variants on ribavirin serum level, hemoglobin drop and therapeutic response in patients with HCV infection. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0032-1322379
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