CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
FATP4 stimulates JNK activation via ER stress and Rac1/MLK3/p-MKK7 signaling leading to enhanced lipoapoptosis
DOI 10.1055/s-0032-1323941
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Nachweis in CareLit
Autor:innenJ Seeßle, G Liebisch, G Schmitz, W Stremmel, W Chamulitrat
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
In non-alcoholic steatohepatitis (NASH), saturated fatty acids injure hepatocytes by inducing apoptosis. It has been reported that inhibitors of fatty acyl-CoA synthetases inhibit palmitate-induced apoptosis. While the functions of FATP4 in the liver are not known, we aim to study the mechanisms of FATP4 on lipoapoptosis in liver cells, and whether FATP4 directs hepatic lipid metabolism to specific pathways. We gene…
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Zitierempfehlung
J Seeßle, G Liebisch, G Schmitz, W Stremmel, W Chamulitrat (2012) FATP4 stimulates JNK activation via ER stress and Rac1/MLK3/p-MKK7 signaling leading to enhanced lipoapoptosis. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0032-1323941
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