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Toll-like receptor-activated primary human hepatocytes produce inflammatory cytokines and different types of interferon, resulting in HCV suppression in a co-culture model

R Bröring, M Lutterbeck, K Kleinehr, A Paul, G Gerken, JF Schlaak · Zeitschrift für Gastroenterologie · Ausgabe 08/2012

DOI 10.1055/s-0032-1323947

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Autor:innenR Bröring, M Lutterbeck, K Kleinehr, A Paul, G Gerken, JF Schlaak
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2012
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Aims: The function of the hepatic innate immune system and its role in the defence against Hepatitis C Virus infection are not well understood. Recent publications suggested that type-III interferons (IFN; Interleukin-28A, -28B and -29) play a crucial role in the host response against HCV. Aim of this study was to investigate the Toll-like receptor (TLR) signaling in primary human hepatocytes and the capacity of the…

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R Bröring, M Lutterbeck, K Kleinehr, A Paul, G Gerken, JF Schlaak (2012) Toll-like receptor-activated primary human hepatocytes produce inflammatory cytokines and different types of interferon, resulting in HCV suppression in a co-culture model. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0032-1323947

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