CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Mice on a high-fat, high-fructose diet and treated with low dose streptozotocin develop features of human NASH
DOI 10.1055/s-0032-1323971
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Autor:innenYO Kim, M Stoll, B Hebich, S Weng, X Wang, D Schuppan
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2012
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: An improved model of human non-alcoholic steatohepatitis (NASH) is needed. To this aim we combined a recent model of a high-fructose/high fat diet with low dose Streptozotocin (STZ) to induce hyperglycemia with hyperinsulinemia but relative insulin resistance (IR). Methods: Six week old female C57BL/6 mice were assigned to standard chow (13% kcal from fat; 65% kcal from complex carbohydrates, n=10), or…
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Zitierempfehlung
YO Kim, M Stoll, B Hebich, S Weng, X Wang, D Schuppan (2012) Mice on a high-fat, high-fructose diet and treated with low dose streptozotocin develop features of human NASH. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0032-1323971
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