CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Assessment of virotherapy resistance phenomena with subsequent evaluation of means helping to overcome such resistancies
DOI 10.1055/s-0032-1324016
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Autor:innenM Noll, S Berchtold, J Lampe, NP Malek, M Bitzer, UM Lauer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Measles vaccine virus (MeV) has shown to possess profound oncolytic capability. However, tumor resistances to MeV might endanger broad clinical success, a hypothesis which is underlined by our analysis of the NCI-60 tumor cell panel being infected with a suicide gene-armed vector (MeV ld-SCD); this SCD suicide gene locally converts the non-toxic prodrug 5-fluorocytosine (5-FC) into the cytotoxic chemot…
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Zitierempfehlung
M Noll, S Berchtold, J Lampe, NP Malek, M Bitzer, UM Lauer (2012) Assessment of virotherapy resistance phenomena with subsequent evaluation of means helping to overcome such resistancies. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0032-1324016
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