CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The Lgr5 positive intestinal stem cell signature
DOI 10.1055/s-0032-1324022
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Autor:innenDE Stange, J Munoz, AJR Heck, H Clevers
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2012
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
In this study, we used transcriptomics and proteomics to define the molecular signature of murine Lgr5 positive intestinal stem cells. Using flow cytometry, we sorted GFP positive cells from Lgr5-EGFP-ires-CreERT2 knock-in mice, profiled the mRNA signature with two array platforms and correlated the transcriptional signature to protein levels measured by quantitative Mass-Spectometry. Combining the three datasets, a…
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Zitierempfehlung
DE Stange, J Munoz, AJR Heck, H Clevers (2012) The Lgr5 positive intestinal stem cell signature. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0032-1324022
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