CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The Hedgehog signalling pathway: A novel therapeutic target for cholangiocellular carcinoma
DOI 10.1055/s-0032-1324038
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Nachweis in CareLit
Autor:innenM El Khatib, A Kalnytska, V Palagani, U Kossatz, M Manns, L Wilkens, N Malek, R Plentz
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: The Hedgehog (Hh) signalling pathway is an important developmental pathway that is aberrant in many cancers. However, the role of this signalling pathway in the carcinogenesis of Cholangiocarcinoma (CCC) is still unknown. Aims: Here, we investigated the effects of Hh inhibition by Cyclopamine in vivo using a Xenograft mouse model and in cultured human CCC cell lines. Methods: We analyzed the effect of…
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Zitierempfehlung
M El Khatib, A Kalnytska, V Palagani, U Kossatz, M Manns, L Wilkens, N Malek, R Plentz (2012) The Hedgehog signalling pathway: A novel therapeutic target for cholangiocellular carcinoma. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0032-1324038
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