CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Protein Kinase D2 controls pancreatic cancer cell invasion by secretion of trypsins PRSS1 and 3 as well as matrix-metalloproteases
DOI 10.1055/s-0032-1324052
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Nachweis in CareLit
Autor:innenT Eiseler, C Köhler, T Seufferlein
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The elucidation of signaling pathways regulating pancreatic cancer cell invasive properties is pivotal to control and develop strategies against metastasis. Protein Kinase D2 (PKD2) is strongly expressed in pancreatic cancer cells. We have recently identified PKD2 as a key regulator of trypsin (PRSS1, PRSS3) as well as matrix-metalloprotease (MMP) secretion in pancreatic cancer cells. PKD2 enhances PRSS1 and 3 expre…
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Zitierempfehlung
T Eiseler, C Köhler, T Seufferlein (2012) Protein Kinase D2 controls pancreatic cancer cell invasion by secretion of trypsins PRSS1 and 3 as well as matrix-metalloproteases. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0032-1324052
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