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Loss of ATM increases cancer formation in a mouse model of human pancreatic ductal adenocarcinoma

A Kleger, R Russell, L Perkhofer, KL Rudolph, M Wagner · Zeitschrift für Gastroenterologie · Ausgabe 08/2012

DOI 10.1055/s-0032-1324068

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Autor:innenA Kleger, R Russell, L Perkhofer, KL Rudolph, M Wagner
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2012
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer deaths in the developed world, with a 5 year survival rate as low as 5%. In recent years, genetically engineered animal models of pancreatic cancer which recapitulate the human disease have provided a useful means of studying both the morphological and molecular features associated with PDAC. The most commonly studied model to date has be…

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A Kleger, R Russell, L Perkhofer, KL Rudolph, M Wagner (2012) Loss of ATM increases cancer formation in a mouse model of human pancreatic ductal adenocarcinoma. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0032-1324068

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