CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
IRF3 KO mice are protected from polymicrobial sepsis by an MIP-2 dependent mechanism
DOI 10.1055/s-0032-1324111
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Autor:innenMT Chiriac, J Yu, MF Neurath, J Mudter
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Interferon regulatory factors (IRFs) play diverse roles in innate and adaptive immunity by promoting type I interferon production and regulating the function of interferon-induced genes that are implicated in chemokine or cytokine production. We have previously reported that IRF3 but not IRF7 deficiency protects mice from bacterial-induced sepsis. Methods: In the present study, we aimed at investigatin…
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Zitierempfehlung
MT Chiriac, J Yu, MF Neurath, J Mudter (2012) IRF3 KO mice are protected from polymicrobial sepsis by an MIP-2 dependent mechanism. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0032-1324111
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