CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Identification of DMBT1 single nucleotide polymorphisms and their haplotypes as novel susceptibility variants for Crohn's disease and ulcerative colitis influencing DMBT1 expression via the transcription factors CREB1 and ATF-2
DOI 10.1055/s-0032-1324115
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Diegelmann, E Le Bras, A Franke, J Glas, S Brand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: DMBT acts as pattern recognition and scavenger receptor with antibacterial properties. Recently, we identified DMBT1 as a target gene of the proinflammatory but also epithelial-protective cytokines IL-22 and IL-27. This candidate gene study with tagging SNPs analyzed the role of DMBT1 gene variants regarding Crohn's disease (CD) and ulcerative colitis (UC) susceptibility. Methods: Seven single nucleotide polym…
Zitieren
Zitierempfehlung
J Diegelmann, E Le Bras, A Franke, J Glas, S Brand (2012) Identification of DMBT1 single nucleotide polymorphisms and their haplotypes as novel susceptibility variants for Crohn's disease and ulcerative colitis influencing DMBT1 expression via the transcription factors CREB1 and ATF-2. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0032-1324115
Mit CareLit weiterarbeiten