CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Verapamil enhances the antiproliferative effect of chemotherapeutic reagents and inhibits tumor growth of chemoresistant side population in pancreatic cancer
DOI 10.1055/s-0032-1324233
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Autor:innenL Zhao, Y Zhao, B Schwarz, J Mysliwietz, P Camaj, Q Bao, JW Jauch, PJ Nelson, M Guba, JW Ellwart, CJ Bruns, AG Bruns
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2012
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: Verapamil is an L-type calcium channel blocker and has been used in the treatment of hypertension, angina pectoris, cardiac arrhythmia, and most recently, cluster headaches. Increasing evidence shows that Verapamil is able to enhance the cytotoxic effect of certain chemotherapies and reverse multidrug resistance by competitively inhibiting drug transport through P-glycoprotein. The side population (SP)…
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Zitierempfehlung
L Zhao, Y Zhao, B Schwarz, J Mysliwietz, P Camaj, Q Bao, JW Jauch, PJ Nelson, M Guba, JW Ellwart, CJ Bruns, AG Bruns (2012) Verapamil enhances the antiproliferative effect of chemotherapeutic reagents and inhibits tumor growth of chemoresistant side population in pancreatic cancer. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0032-1324233
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