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House dust mite-induced ATP release plays a role in the innate immunological response and barrier dysfunction of airway epithelium

S Post, M Nawijn, A van Oosterhout, I Heijink · Pneumologie · Ausgabe 11/2012

DOI 10.1055/s-0032-1329799

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Autor:innenS Post, M Nawijn, A van Oosterhout, I Heijink
ZeitschriftPneumologie
Ausgabe11/2012
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: House dust mite (HDM) affects both the barrier and the innate immune functions of the airway epithelium. The release of ATP upon HDM administration has been shown to be critically required for allergic sensitization, airway remodeling and eosinophilic inflammation in a mouse model. Objective: We sought to determine the role of ATP release in the HDM-induced altered barrier function and innate immune resp…

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Zitierempfehlung

S Post, M Nawijn, A van Oosterhout, I Heijink (2012) House dust mite-induced ATP release plays a role in the innate immunological response and barrier dysfunction of airway epithelium. Pneumologie (11). https://doi.org/10.1055/s-0032-1329799

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