CareLit · DOI-Nachweis · Pneumologie
Recognition of a molecular defect in bronchial epithelial cells from 70% of mild asthmatics
DOI 10.1055/s-0032-1329801
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Chowdhury, A Dijkhuis, J van der Zee, R Lutter
ZeitschriftPneumologie
Ausgabe11/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Interleukin-17 (IL-17) synergizes with pro-inflammatory stimuli like TNF-α in an exaggerated production of inflammatory mediators by human primary bronchial epithelial cells (PBEC) which relates to a decreased decay of mRNAs encoding these inflammatory mediators. Recently, we have found that IL-17 coordinately attenuates both the ARE-mediated pathway of mRNA decay and that mediated by microRNA 16 (submitted). Since…
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Zitierempfehlung
S Chowdhury, A Dijkhuis, J van der Zee, R Lutter (2012) Recognition of a molecular defect in bronchial epithelial cells from 70% of mild asthmatics. Pneumologie (11). https://doi.org/10.1055/s-0032-1329801
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