CareLit · DOI-Nachweis · Pneumologie
Influence of Phosphodiesterase-Inhibitor PDE4 Roflumilast N-Oxide on Surfactant Protein of human Alveolar Epithelial Cell Type II
DOI 10.1055/s-0032-1329802
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK Hoehne, SJ Schließmann, A Kirschbaum, T Ploenes, J Müller-Quernheim, H Tenor, G Zissel
ZeitschriftPneumologie
Ausgabe11/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Surfactant Proteins (SPs) are surface active lipoproteins, essential for the integrity of the lung and important for host defence. All four Surfactant Proteins (A-D) and their isoforms are mainly expressed by alveolar epithelial cells type II (AECII). It has been shown that SP gene transcription is regulated by intracellular cyclic adenosine monophosphate (cAMP). Phosphodiesterase 4 is the major hydrolysing phosphod…
Zitieren
Zitierempfehlung
K Hoehne, SJ Schließmann, A Kirschbaum, T Ploenes, J Müller-Quernheim, H Tenor, G Zissel (2012) Influence of Phosphodiesterase-Inhibitor PDE4 Roflumilast N-Oxide on Surfactant Protein of human Alveolar Epithelial Cell Type II. Pneumologie (11). https://doi.org/10.1055/s-0032-1329802
Mit CareLit weiterarbeiten