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P2Y6 receptor signalling in COPD patients and cigarette smoke-exposed mice

K Bracke, K Ayata, S Cicko, M Lucatelli, D Ferrari, C Virchow, G Lungarella, R Koczulla, G Brusselle, M Idzko · Pneumologie · Ausgabe 11/2012

DOI 10.1055/s-0032-1329806

Bibliografische Angaben

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Autor:innenK Bracke, K Ayata, S Cicko, M Lucatelli, D Ferrari, C Virchow, G Lungarella, R Koczulla, G Brusselle, M Idzko
ZeitschriftPneumologie
Ausgabe11/2012
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Rationale: Extracellular ATP, via activation of the purinergic receptor subtypes P2Y2 and P2X7, has been identified as a new player in the pathogenesis of chronic obstructive pulmonary disease (COPD) and cigarette smoke (CS)-induced lung inflammation. Recent evidence suggests involvement of the UDP/P2Y6R axis in inflammatory lung diseases; however its role in COPD needs to be elucidated. Objectives: To explore the r…

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Zitierempfehlung

K Bracke, K Ayata, S Cicko, M Lucatelli, D Ferrari, C Virchow, G Lungarella, R Koczulla, G Brusselle, M Idzko (2012) P2Y6 receptor signalling in COPD patients and cigarette smoke-exposed mice. Pneumologie (11). https://doi.org/10.1055/s-0032-1329806

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