CareLit · DOI-Nachweis · Pneumologie
Silica-induced inflammasome activation in lung epithelial cells
DOI 10.1055/s-0032-1329815
Bibliografische Angaben
Nachweis in CareLit
Autor:innenPM Peeters, NL Reynaert, TN Perkins, BT Mossmann, EF Wouters
ZeitschriftPneumologie
Ausgabe11/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction and objectives: In myeloid cells the inflammasome plays a crucial role in innate immune defenses against pathogen- and danger-associated patterns such as crystalline silica. Respirable mineral particles impinge upon the lung epithelium causing irreversible damage, sustained inflammation and silicosis. In this study we investigated lung epithelial cells as a target for silica-induced inflammasome activat…
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Zitierempfehlung
PM Peeters, NL Reynaert, TN Perkins, BT Mossmann, EF Wouters (2012) Silica-induced inflammasome activation in lung epithelial cells. Pneumologie (11). https://doi.org/10.1055/s-0032-1329815
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