CareLit · DOI-Nachweis · Pneumologie
Protective effect of mesenchymal stem cells des (MSC) on hypoxia induced epithelial to mesenchymal transition (EMT) of alveolar epithelial cells (AEC)
DOI 10.1055/s-0032-1329816
Bibliografische Angaben
Nachweis in CareLit
Autor:innenY Uzunhan, N Randrianarison, D Marchant, N Dard, J Larghero, C Planes
ZeitschriftPneumologie
Ausgabe11/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The current paradigm suggests a central role of the epithelium in pulmonary fibrosis pathogenesis and progression. Hypoxia may promote myofibroblasts accumulation by facilating EMT. In animal models of lung fibrosis, administration of bone marrow derived MSC may reduce fibrosis and mortality. We hypothesized that MSC may favor alveolar wound healing by preventing hypoxia-induced EMT. We examined the role of hypoxia…
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Zitierempfehlung
Y Uzunhan, N Randrianarison, D Marchant, N Dard, J Larghero, C Planes (2012) Protective effect of mesenchymal stem cells des (MSC) on hypoxia induced epithelial to mesenchymal transition (EMT) of alveolar epithelial cells (AEC). Pneumologie (11). https://doi.org/10.1055/s-0032-1329816
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