Stem cells in neonatal brain disorders

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Perinatal hypoxic-ischemic injury (HII) with subsequent neonatal encephalopathy remains a major cause of long-term adverse neurological outcome. Hypothermia has recently been shown to protect infants with moderate encephalopathy. However, a large number of patients still survive with severe deficits and additional therapies are highly warranted. Furthermore, hypothermia has not been sufficiently investigated in pret…

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