CareLit · DOI-Nachweis · Klinische Pädiatrie
Intrapulmonary delivery of human umbilical cord mesenchymal stem cells attenuates acute lung injury by expanding CD4+CD25+forkhead boxp3 (FOXP3)+regulatory T cells and balancing anti- and pro-inflammatory factors
DOI 10.1055/s-0032-1330787
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Nachweis in CareLit
Autor:innenR Wu, J Sun, ZC Han
ZeitschriftKlinische Pädiatrie
Ausgabe11/2012
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background: Systemic and local inflammatory processes have a key, mainly detrimental role in the pathophysiology of acute lung injury (ALI). The present study was designed to determine whether human umbilical cord mesenchymal stem cells (UCMSC) are able to act on CD4+CD25+Foxp3+Treg cells and lead to an improvement in ALI. Methods: Mice were administered intratracheally endotoxin (lipopolysaccharide [LPS]) and recei…
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Zitierempfehlung
R Wu, J Sun, ZC Han (2012) Intrapulmonary delivery of human umbilical cord mesenchymal stem cells attenuates acute lung injury by expanding CD4+CD25+forkhead boxp3 (FOXP3)+regulatory T cells and balancing anti- and pro-inflammatory factors. Klinische Pädiatrie (11). https://doi.org/10.1055/s-0032-1330787
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