CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Hepatic accumulation of IL-17 producing γδ T cells via chemokine receptor CCR6 restricts liver inflammation and fibrosis by inhibiting hepatic stellate cells
DOI 10.1055/s-0032-1331898
Bibliografische Angaben
Nachweis in CareLit
Autor:innenL Hammerich, F Heymann, HW Zimmermann, JM Bangen, N Gaßler, S Huss, C Liedtke, I Prinz, SA Lira, T Luedde, C Trautwein, F Tacke
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aim: The chemokine receptor CCR6 is known to be expressed on some T helper cells and γδ T cells, monocyte derived dendritic cells and B cell subsets. It plays an important role in mucosal immunity, but its role in liver disease is largely unknown. In this study we investigated its functional relevance in chronic liver disease and hepatic fibrosis. Methods: Liver inflammation and fibrosis was induced in wildtype (wt)…
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Zitierempfehlung
L Hammerich, F Heymann, HW Zimmermann, JM Bangen, N Gaßler, S Huss, C Liedtke, I Prinz, SA Lira, T Luedde, C Trautwein, F Tacke (2013) Hepatic accumulation of IL-17 producing γδ T cells via chemokine receptor CCR6 restricts liver inflammation and fibrosis by inhibiting hepatic stellate cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1331898
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