CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
In vivo RNAi screening identified MKK4 as a new therapeutic target for the improvement of liver regeneration
DOI 10.1055/s-0032-1331899
Bibliografische Angaben
Nachweis in CareLit
Autor:innenT Wuestefeld, M Pesic, T Longerich, TW Kang, T Yevsa, D Dauch, A Potapova, R Rudalska, I Rittelmeyer, M Jarek, R Geffers, M Scharfe, F Klawonn, NP Malek, P Schirmacher, M Ott, A Vogel, MP Manns, L Zender
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
We established a unique system for performing direct in vivo RNAi screens to genetically dissect cellular signaling networks that regulate proliferation control of hepatocytes during liver damage and regeneration. By combining the well characterized FAH-/- mouse model with a transposon based vector system, we generated chimeric mouse livers. In these mouse livers each hepatocyte expresses FAH, a marker gene and a mi…
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Zitierempfehlung
T Wuestefeld, M Pesic, T Longerich, TW Kang, T Yevsa, D Dauch, A Potapova, R Rudalska, I Rittelmeyer, M Jarek, R Geffers, M Scharfe, F Klawonn, NP Malek, P Schirmacher, M Ott, A Vogel, MP Manns, L Zender (2013) In vivo RNAi screening identified MKK4 as a new therapeutic target for the improvement of liver regeneration. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1331899
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