CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Notch2 converts hepatoblasts and adult hepatocytes to the biliary lineage via canonical Notch signalling independent of Hes1 in mice
DOI 10.1055/s-0032-1331900
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Autor:innenP Jeliazkova, S Jörs, M Lee, U Zimber-Strobl, J Ferrer, RM Schmid, JT Siveke, F Geisler
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Notch signaling via the Notch2 receptor is essential for normal biliary tubulogenesis during liver development. However, the signaling events downstream of Notch2 critical for this process are less well defined. Furthermore, whether Notch signaling also underlies adult hepatic cell fate decisions is largely unknown. By implementing different genetic mouse models, we provide a comprehensive analysis that defines the…
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Zitierempfehlung
P Jeliazkova, S Jörs, M Lee, U Zimber-Strobl, J Ferrer, RM Schmid, JT Siveke, F Geisler (2013) Notch2 converts hepatoblasts and adult hepatocytes to the biliary lineage via canonical Notch signalling independent of Hes1 in mice. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1331900
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