CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Functional effects of methylthioadenosine phosphorylase (MTAP) expression in chronic liver disease
DOI 10.1055/s-0032-1331911
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Autor:innenB Czech, D Valletta, K Dettmer, M Müller, A Bosserhoff, P Oefner, C Hellerbrand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The polyamine metabolic pathway has been implicated in the pathogenesis of chronic liver disease. Methylthioadenosine phosphorylase (MTAP) the rate-limiting enzyme in the methionine and adenine salvage pathway catalyzes the phosphorylation of 5'-deoxy-5'-(methylthio)adenosine (MTA), which is a by-product of polyamine synthesis. The aim of this study was to assess MTAP expression and function in chronic liver disease…
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Zitierempfehlung
B Czech, D Valletta, K Dettmer, M Müller, A Bosserhoff, P Oefner, C Hellerbrand (2013) Functional effects of methylthioadenosine phosphorylase (MTAP) expression in chronic liver disease. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1331911
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