CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Adenoviral-mediated specific targeting of hepatic stellate cells as a selective therapeutic approach in liver fibrosis
DOI 10.1055/s-0032-1331916
Bibliografische Angaben
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Autor:innenB Genz, J Reetz, C Meier, BS Kowtharapu, A Stoll, F Timm, B Vollmar, B Pützer, K Abshagen, O Herchenröder
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
*equal contribution The activation of hepatic stellate cells (HSCs) is a central pathological process in the development of liver fibrosis. Thus, activated HSCs are attractive targets for antifibrotic therapies. We established an adenoviral based gene transfer system for the selective transduction of HSCs by linking a HSC-specific peptide to the virus envelope. The NGFp peptide displays a part of the nerve growth fa…
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Zitierempfehlung
B Genz, J Reetz, C Meier, BS Kowtharapu, A Stoll, F Timm, B Vollmar, B Pützer, K Abshagen, O Herchenröder (2013) Adenoviral-mediated specific targeting of hepatic stellate cells as a selective therapeutic approach in liver fibrosis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1331916
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