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Adult HNF1beta+ cells give rise to oval cells but do not significantly contribute to normal homeostasis or injury repair of hepatocytes in mice

S Jörs, P Jeliazkova, M Ringelhan, J Ferrer, RM Schmid, JT Siveke, F Geisler · Zeitschrift für Gastroenterologie · Ausgabe 01/2013

DOI 10.1055/s-0032-1331923

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Autor:innenS Jörs, P Jeliazkova, M Ringelhan, J Ferrer, RM Schmid, JT Siveke, F Geisler
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

In response to liver injury or loss of liver mass, hepatocytes and cholangiocytes proliferate to replace the injured tissue. However, in case of chronic liver and biliary disease, when hepatocyte and cholangiocyte proliferation is impaired, an expansion of small putative progenitors is observed (oval cell response). Oval cells reside in a niche close to the terminal bile ducts, called canals of Hering, and are belie…

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S Jörs, P Jeliazkova, M Ringelhan, J Ferrer, RM Schmid, JT Siveke, F Geisler (2013) Adult HNF1beta+ cells give rise to oval cells but do not significantly contribute to normal homeostasis or injury repair of hepatocytes in mice. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1331923

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