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Next generation sequencing of the Ago2 interacting transcriptome identified chemokine family members as novel targets of neuronal microRNAs in hepatic stellate cells

A Noetel, N Elfimova, D Becker, P Nürnberg, A Teufel, HE Wasmuth, HP Dienes, M Odenthal · Zeitschrift für Gastroenterologie · Ausgabe 01/2013

DOI 10.1055/s-0032-1331937

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Autor:innenA Noetel, N Elfimova, D Becker, P Nürnberg, A Teufel, HE Wasmuth, HP Dienes, M Odenthal
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben

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Background: After myofibroblastic transdifferentiation hepatic stellate cells (HSC), mainly involved in liver fibrosis by extracellular matrix production, exhibit an altered growth factor profile including increased expression of neuronal mediators. Here, we analyzed putative targets of neuronal microRNAs miR-9, miR-125b, and miR-128 by deep sequencing of the transcript population, interacting with miRNA/Argonaute 2…

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A Noetel, N Elfimova, D Becker, P Nürnberg, A Teufel, HE Wasmuth, HP Dienes, M Odenthal (2013) Next generation sequencing of the Ago2 interacting transcriptome identified chemokine family members as novel targets of neuronal microRNAs in hepatic stellate cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1331937

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