CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Role of protein turnover in NF-κB signalling: A systems biology study on primary hepatocytes
DOI 10.1055/s-0032-1331940
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Nachweis in CareLit
Autor:innenF Pinna, S Sahle, K Beuke, MB Bissinger, S Tuncay, L D'Alessandro, R Gauges, J Timmer, A Raue, U Klingmüller, P Schirmacher, U Kummer, K Breuhahn
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
The cytokine tumor necrosis factor (TNF)-α is a key factor in the priming phase of liver regeneration since it activates the NF-κB signalling pathway, which primes hepatocyte for proliferation. In order to understand how TNFα-dependend NF-κB activation contributes to a cellular response in parenchymal liver cells, we aimed to generate a hepatocyte-specific mathematical model based on quantitative and time-resolved d…
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Zitierempfehlung
F Pinna, S Sahle, K Beuke, MB Bissinger, S Tuncay, L D'Alessandro, R Gauges, J Timmer, A Raue, U Klingmüller, P Schirmacher, U Kummer, K Breuhahn (2013) Role of protein turnover in NF-κB signalling: A systems biology study on primary hepatocytes. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1331940
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