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Hepatocyte specific deletion of Mesenchymal-epithelial transition factor (c-Met) leads to the development of severe non-alcoholic-steatohepatitis (NASH) in a murine NASH model

F Schumacher, M Hatting, N Gaßler, MV Boekschoten, M Müller, KL Streetz, C Trautwein, DC Kroy · Zeitschrift für Gastroenterologie · Ausgabe 01/2013

DOI 10.1055/s-0032-1331949

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Autor:innenF Schumacher, M Hatting, N Gaßler, MV Boekschoten, M Müller, KL Streetz, C Trautwein, DC Kroy
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: One of the fastest growing medical problems in industrial countries is the metabolic syndrome including non-alcoholic-fatty-liver disease (NAFLD). The spectrum of NAFLD includes NASH. NASH is characterized by hepatic fat accumulation leading to an increase of oxidative stress and apoptosis resulting in severe inflammation and finally liver cirrhosis and hepatocellular carcinoma. As a consequence, NASH-re…

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F Schumacher, M Hatting, N Gaßler, MV Boekschoten, M Müller, KL Streetz, C Trautwein, DC Kroy (2013) Hepatocyte specific deletion of Mesenchymal-epithelial transition factor (c-Met) leads to the development of severe non-alcoholic-steatohepatitis (NASH) in a murine NASH model. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1331949

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