CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Heterozygous p53 knockout affects development of obesity, insulin resistance and non-alcoholic steatohepatitis in mice fed with a Western type diet
DOI 10.1055/s-0032-1331950
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Nachweis in CareLit
Autor:innenD Valletta, B Czech, C Hellerbrand, M Müller
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The tumor suppressor p53 is a primary sensor of stressful stimuli. It controls several biologic processes and plays a central role in hepatocarcinogenesis. p53 deficient (p53 -/-) mice spontaneously develop intra- and extra-hepatic malignancies, and recently, it has been shown that they develop less hepatocellular damage and fibrosis upon feeding the NASH-inducing methionine- and choline-deficient (MCD) diet. The ai…
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Zitierempfehlung
D Valletta, B Czech, C Hellerbrand, M Müller (2013) Heterozygous p53 knockout affects development of obesity, insulin resistance and non-alcoholic steatohepatitis in mice fed with a Western type diet. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1331950
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