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Activation by Pathogen- and Damage-Associated Molecular Patterns Regulates the Expression of RANTES in Primary Hepatic Stellate Cells

B Wang, R Broering, CI Real, M Lutterbeck, G Gerken, M Lu, JF Schlaak · Zeitschrift für Gastroenterologie · Ausgabe 01/2013

DOI 10.1055/s-0032-1331952

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Autor:innenB Wang, R Broering, CI Real, M Lutterbeck, G Gerken, M Lu, JF Schlaak
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

While the chemokine RANTES is known to play an important role in the pathogenesis of liver fibrosis, little is known about its regulation by the innate immune system. Therefore, we studied the role of Toll-like receptors (TLRs) and Retinoic acid-inducible gene I (RIG-I) like receptors (RLRs) in the activation of hepatic stellate cells (HSC). Primary isolated murine and human HSCs were stimulated with TLR1–9, RIG-I l…

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B Wang, R Broering, CI Real, M Lutterbeck, G Gerken, M Lu, JF Schlaak (2013) Activation by Pathogen- and Damage-Associated Molecular Patterns Regulates the Expression of RANTES in Primary Hepatic Stellate Cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1331952

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