CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Matrix metalloproteinase 14 (MMP14) over-expression increases invasiveness and engraftment of transplanted hepatocytes
DOI 10.1055/s-0032-1331960
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Autor:innenQ Yuan, J Waern, AD Sharma, MP Manns, M Ott
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background: Hepatocyte transplantation is a promising approach to correct hereditary metabolic liver disease. Our study describes a novel method to increase the invasiveness of transplanted cells by matrix degradation via the over-expression of matrix metalloproteinase 14 (MMP14) in transplanted cells. Methods: The murine Mmp14 gene was cloned from the Hepa1–6 liver tumor cell line and inserted into a lentiviral vec…
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Zitierempfehlung
Q Yuan, J Waern, AD Sharma, MP Manns, M Ott (2013) Matrix metalloproteinase 14 (MMP14) over-expression increases invasiveness and engraftment of transplanted hepatocytes. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1331960
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