CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Drug-induced alterations in the metabolome of primary hepatocytes
DOI 10.1055/s-0032-1331986
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Potratz, A Krüger, S Zellmer, H Jungnickel, J Hengstler, A Luch
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Xenobiotics can induce rapid changes in the metabolome of cells even at non-toxic doses. This might result in the disturbance of metabolite and cell membrane compositions. The latter affects cellular signaling and transport processes. The effect of low, non-toxic doses of acetaminophen on the cell membrane composition was studied in primary hepatocytes, using ToF-SIMS. Methods: Primary rat hepatocytes we…
Zitieren
Zitierempfehlung
S Potratz, A Krüger, S Zellmer, H Jungnickel, J Hengstler, A Luch (2013) Drug-induced alterations in the metabolome of primary hepatocytes. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1331986
Mit CareLit weiterarbeiten