CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Pharmacologic cholinesterase inhibition in a mouse model of acetaminophen-induced acute liver failure
DOI 10.1055/s-0032-1332031
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Nachweis in CareLit
Autor:innenN Steinebrunner, C Mogler, C Sandig, W Stremmel, C Eisenbach
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Acetaminophen is one of the most widely used analgesics. Taken in overdoses, acetaminophen causes acute liver failure (ALF) with widespread hepatocellular necrosis and parenchymal inflammation leading to a systemic inflammatory syndrome. The nervous system, through the vagus nerve, can down-regulate inflammation by decreasing the release of tumor necrosis factor a (TNF-a) by endotoxin-stimulated macrophages. This an…
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Zitierempfehlung
N Steinebrunner, C Mogler, C Sandig, W Stremmel, C Eisenbach (2013) Pharmacologic cholinesterase inhibition in a mouse model of acetaminophen-induced acute liver failure. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332031
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