CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Global alterations of DNA methylation patterns in cholangiocarcinoma target cancer relevant pathways including Wnt/β-catenin signaling
DOI 10.1055/s-0032-1332045
Bibliografische Angaben
Nachweis in CareLit
Autor:innenB Goeppert, C Konermann, C Schmid, O Bogatyrova, L Geiselhart, D Weichenhahn, N Becker, A Mehrabi, M Hafezi, F Klauschen, A Stenzinger, M Renner, A Warth, L Gu, M Zucknick, W Weichert, P Schirmacher, C Plass
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and Aims: The molecular mechanisms underlying the genesis of cholangiocarcinomas (CCs) are poorly understood. Epigenomic changes such as aberrant hypermethylation and subsequent atypical gene expression are characteristic features of most human cancers. In CC, data of global methylation changes are scarce. Methods: We performed a genome-wide analysis for aberrant promoter methylation in human CCs. We prof…
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Zitierempfehlung
B Goeppert, C Konermann, C Schmid, O Bogatyrova, L Geiselhart, D Weichenhahn, N Becker, A Mehrabi, M Hafezi, F Klauschen, A Stenzinger, M Renner, A Warth, L Gu, M Zucknick, W Weichert, P Schirmacher, C Plass (2013) Global alterations of DNA methylation patterns in cholangiocarcinoma target cancer relevant pathways including Wnt/β-catenin signaling. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332045
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