CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Down regulation of Sonic Hedgehog Signaling attenuates carcinogenesis in vitro and increased tumor necrosis in a Xenograft mouse model of cholangiocellular carcinoma
DOI 10.1055/s-0032-1332057
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Nachweis in CareLit
Autor:innenM El Khatib, A Kalnytska, V Palagani, U Kossatz, MP Manns, NP Malek, L Wilkens, RR Plentz
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: The Hedgehog signaling pathway controls cell proliferation and differentiation during embryonic development. Altered activation of Hedgehog has been found and described in different human tumor types. Cholangiocellular carcinoma (CCC) is the second most common primary malignant tumor in the liver. The vast majority of patients with CCC are not good candidates for curative surgery and conventional chemoth…
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Zitierempfehlung
M El Khatib, A Kalnytska, V Palagani, U Kossatz, MP Manns, NP Malek, L Wilkens, RR Plentz (2013) Down regulation of Sonic Hedgehog Signaling attenuates carcinogenesis in vitro and increased tumor necrosis in a Xenograft mouse model of cholangiocellular carcinoma. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332057
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