CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Downregulation of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) in human cholangiocellular carcinoma and their prognostic significance
DOI 10.1055/s-0032-1332062
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Nachweis in CareLit
Autor:innenA Graesel, A Lautem, M Heise, J Knapstein, JM Schattenberg, G Otto, H Lang, PR Galle, M Schuchmann, T Zimmermann
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: The cholangiocellular carcinoma (CCC) is a primary hepatic malignancy derived from cholangiocytes. The prognosis for CCC is very poor and conventional chemotherapy is not effective in prolonging long-term patient survival rates. The organic cation transporters OCT1 and OCT3 mediate the transport of a broad spectrum of endogenous substrates and the detoxification of xenobiotics. Moreover, OCTs are held…
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Zitierempfehlung
A Graesel, A Lautem, M Heise, J Knapstein, JM Schattenberg, G Otto, H Lang, PR Galle, M Schuchmann, T Zimmermann (2013) Downregulation of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) in human cholangiocellular carcinoma and their prognostic significance. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332062
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