CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Effects of the mTOR inhibitor RAD001, the dual mTOR and PI3-kinase inhibitor BEZ235 and the PI3-kinase inhibitor BKM120 on HCC
DOI 10.1055/s-0032-1332073
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Autor:innenMM Kirstein, AE Boukouris, D Pothiraju, LE Buitrago-Molina, S Marhenke, J Orlik, MP Manns, A Vogel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: Hepatocellular carcinoma (HCC) is one of the most deadly cancers worldwide with only few therapeutic options for patients with advanced disease. Aberrant mTOR signaling has been identified in up to 50–60% of cases of hepatocellular carcinoma and therefore represents a promising target for novel therapeutic approaches. This study evaluated the anti-tumor effect of the mTOR inhibitor RAD001, the dual PI3…
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Zitierempfehlung
MM Kirstein, AE Boukouris, D Pothiraju, LE Buitrago-Molina, S Marhenke, J Orlik, MP Manns, A Vogel (2013) Effects of the mTOR inhibitor RAD001, the dual mTOR and PI3-kinase inhibitor BEZ235 and the PI3-kinase inhibitor BKM120 on HCC. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332073
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