CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
An oncolytic measles vaccine virus armed with a suicide gene eliminates human hepatoma cells independently of apoptosis
DOI 10.1055/s-0032-1332079
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Autor:innenJ Lampe, S Bossow, T Weiland, IP Smirnow, R Lehmann, WM Neubert, M Bitzer, UM Lauer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and Aims: Due to late diagnosis and a pronounced chemoresistance, most patients with hepatocellular carcinoma (HCC) have an overall poor prognosis. Oncolytic Measles vaccine viruses (MeV) have been shown to possess anti-tumor properties and their efficacy has been enhanced by arming with suicide genes. Here, we sought to test suicide gene-armed oncolytic MeV for the virotherapeutic treatment of HCC and to…
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Zitierempfehlung
J Lampe, S Bossow, T Weiland, IP Smirnow, R Lehmann, WM Neubert, M Bitzer, UM Lauer (2013) An oncolytic measles vaccine virus armed with a suicide gene eliminates human hepatoma cells independently of apoptosis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332079
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