CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
p21 regulates liver progenitor cell activation and hepatocarcinogenesis in inflammation-associated liver disease
DOI 10.1055/s-0032-1332082
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Autor:innenS Marhenke, LE Buitrago-Molina, J Endig, J Lamlé, T Longerich, R Geffers, C Dorrell, A Lechel, SF Katz, MP Manns, A Vogel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Given the poor prognosis in metastatic stage of the disease, new therapies are urgently needed. Previously it has been shown that loss of the cell-cycle regulator p21 dramatically accelerates hepatocarcinogenesis suggesting that p21 acts as tumor suppressor. In order to determine the impact of p21 in inflammation-induced carcinog…
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Zitierempfehlung
S Marhenke, LE Buitrago-Molina, J Endig, J Lamlé, T Longerich, R Geffers, C Dorrell, A Lechel, SF Katz, MP Manns, A Vogel (2013) p21 regulates liver progenitor cell activation and hepatocarcinogenesis in inflammation-associated liver disease. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332082
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