CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Development of an orthotopic HCC mouse model for analysis of tumor-specific CD8 T cell responses
DOI 10.1055/s-0032-1332087
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Autor:innenD Ostroumov
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
In order to study the influence of hepatocellular carcinoma on cytotoxic CD8 T cells we have established an orthotopic HCC mouse model. Hepatic tumors were established in vivo using the „Sleeping beauty“ transposon system. Hydrodynamic injection was used to facilitate transfection of murine hepatocytes with the plasmids that contain cDNA coding for oncogenes. After the SB transposase achieved integration of the onco…
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Zitierempfehlung
D Ostroumov (2013) Development of an orthotopic HCC mouse model for analysis of tumor-specific CD8 T cell responses. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332087
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