CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Clear cell foci of altered hepatocytes and hepatocellular carcinomas in the N-Nitrosomorpholine (NNM) model in the rat show an overexpression of pro-oncogenic pathways and metabolic alterations similar to lesions in the islet-transplantati…
DOI 10.1055/s-0032-1332092
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Ribback, DF Calvisi, A Cigliano, V Sailer, CD Heidecke, M Birth, F Dombrowski
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aims: Administration of the N-Nitrosamine N-Nitrosomorpholine (NNM) in rats is a well examined model of chemically induced hepatocarcinogenesis and starts with the formation of focal pre-neoplastic lesions in the liver, i.e. clear cell foci (CCF) of altered hepatocytes, and induces the formation of hepatocellular adenomas (HCA) and carcinomas (HCC). Similar lesions are known in the rat model of insuli…
Zitieren
Zitierempfehlung
S Ribback, DF Calvisi, A Cigliano, V Sailer, CD Heidecke, M Birth, F Dombrowski (2013) Clear cell foci of altered hepatocytes and hepatocellular carcinomas in the N-Nitrosomorpholine (NNM) model in the rat show an overexpression of pro-oncogenic pathways and metabolic alterations similar to lesions in the islet-transplantation model. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332092
Mit CareLit weiterarbeiten