CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Liver specific deletion of CYLDexon7/8 in mice leads to ductular reaction, oval cell activation and increased hepatocellular proliferation after partial hepatectomy
DOI 10.1055/s-0032-1332100
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Nachweis in CareLit
Autor:innenT Urbanik, T Longerich, K Becker, N Hövelmeyer, M Schuchmann, D Jäger, A Waisman, MA Wörns, H Schulze-Bergkamen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: The NF-κB pathway is constitutively activated in various types of cancers and represents a mechanistic link between anti-apoptotic signaling, proliferation and cancer development. NF-κB signaling is negatively controlled by ubiquitin deconjugation mediated by deubiquitinases such as CYLD and A20. The tumor suppressor CYLD is frequently downregulated in hepatocellular carcinoma (HCC), thereby contributing…
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Zitierempfehlung
T Urbanik, T Longerich, K Becker, N Hövelmeyer, M Schuchmann, D Jäger, A Waisman, MA Wörns, H Schulze-Bergkamen (2013) Liver specific deletion of CYLDexon7/8 in mice leads to ductular reaction, oval cell activation and increased hepatocellular proliferation after partial hepatectomy. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332100
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