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Neutral effects of common variation in the hepatocanalicular phosphatidylcholine transporter ABCB4 and the bile salt export pump ABCB11 on genetic cholangiocarcinoma risk

V Zimmer, A Höblinger, F Mihalache, M Krawczyk, F Grünhage, M Acalovschi, F Lammert · Zeitschrift für Gastroenterologie · Ausgabe 01/2013

DOI 10.1055/s-0032-1332111

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Autor:innenV Zimmer, A Höblinger, F Mihalache, M Krawczyk, F Grünhage, M Acalovschi, F Lammert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben

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Background: The pathogenesis of cholangiocarcinoma (CCA) as the second most common primary liver cancer is poorly characterized. However, the combined effects of inflammation and/or cholestasis are considered to be central to CCA formation. Whereas information on inherited risk factors underlying CCA susceptibility is limited, genetic variation in hepatobiliary transporters has been suggested to modulate genetic ris…

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V Zimmer, A Höblinger, F Mihalache, M Krawczyk, F Grünhage, M Acalovschi, F Lammert (2013) Neutral effects of common variation in the hepatocanalicular phosphatidylcholine transporter ABCB4 and the bile salt export pump ABCB11 on genetic cholangiocarcinoma risk. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332111

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