CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Continuous Toll-like receptor 3 activation in primary human hepatocytes, mimicking chronic hepatitis C infection, leads to hyper-responsiveness to poly I:C in vitro
DOI 10.1055/s-0032-1332119
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Autor:innenR Broering, M Lutterbeck, K Kleinehr, M Trippler, A Paul, G Gerken, JF Schlaak
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aim: Chronic hepatitis C infection is associated with elevated expression of interferon sensitive genes (ISGs) in the liver, which should limit viral replication, but correlates with the non-response to interferon (IFN) based therapies. Recent data suggested that type-III interferons (IFN; Interleukin (IL-) 28A, -28B and 29) may play an important role in the defense of HCV. Aim of this study was to investigate the T…
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Zitierempfehlung
R Broering, M Lutterbeck, K Kleinehr, M Trippler, A Paul, G Gerken, JF Schlaak (2013) Continuous Toll-like receptor 3 activation in primary human hepatocytes, mimicking chronic hepatitis C infection, leads to hyper-responsiveness to poly I:C in vitro. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332119
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