CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Induction of Sustained Tolerance towards Experimental ConA Hepatitis Depends on CD4+ T and NKT Cells
DOI 10.1055/s-0032-1332122
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Autor:innenB Claass, A Erhardt, G Tiegs
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Objective: In mice, a single i.v. injection of the T cell mitogen Concanavalin A (ConA) leads to severe acute T cell and Kupffer Cell (KC) dependent hepatitis. Following a sublethal treatment of ConA, mice develop resistance towards hepatitis after additional ConA injections within 8 days. This resistance is characterized by regulatory T cell and KC derived IL-10 dependent immunoregulation. However, IL-10 production…
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Zitierempfehlung
B Claass, A Erhardt, G Tiegs (2013) Induction of Sustained Tolerance towards Experimental ConA Hepatitis Depends on CD4+ T and NKT Cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332122
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