CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
NKT cell activation influences hepatic immunity by interfering with cross-presentation in liver sinusoidal endothelial cells
DOI 10.1055/s-0032-1332125
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Autor:innenL Diehl, JP Böttcher, N von Oppen, C Metzger, S Hegenbarth, G Wingender, C Kurts, B Höchst, D Wohlleber, PA Knolle
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Natural Killer T (NKT) cells are a predominant lymphoid cell population in the liver. They are specifically recruited to the liver via CXCR6 and migrate through the liver sinusoids along liver sinusoidal endothelial cells (LSEC). We have previously shown that LSEC can cross-present soluble antigens on MHC I molecules to CD8 T cells causing a functionally inert state. We now show that LSEC express CD1d and can presen…
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Zitierempfehlung
L Diehl, JP Böttcher, N von Oppen, C Metzger, S Hegenbarth, G Wingender, C Kurts, B Höchst, D Wohlleber, PA Knolle (2013) NKT cell activation influences hepatic immunity by interfering with cross-presentation in liver sinusoidal endothelial cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332125
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